| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 483.95 |
| stddev | 830.3 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland; day and night; and mixed tissue, day; polyA
Rat
(experiment details)Pineal; Lhx4, Bsx
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 38.17 |
| stddev | 9.69 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland development; day and night
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 365.71 |
| stddev | 472.17 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland (RP), retina (RR) and mixed tissue (RX); 24-hr time series
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 322.55 |
| stddev | 661.09 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland; day and night; and mixed tissue, day; Ribominus
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 65.78 |
| stddev | 112.61 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland; superior cervical decentralization (DCN) or ganglionectomy (SCGX); day and night
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 179.26 |
| stddev | 203.7 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland in vitro; norepinephrine (NE) or dibutyl cyclic AMP (DBcAMP)
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 73.43 |
| stddev | 55.95 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |
Pineal gland marker genes; day and night
Rat
(experiment details)| gene | ENSRNOG00000011182 |
|---|---|
| gene name | Aanat |
| gene biotype | protein_coding |
| chrom | chr10 |
| mean | 265.43 |
| stddev | 453.91 |
| Official full name | aralkylamine N-acetyltransferase |
| Summary | The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014] |
| gene id | ENSRNOG00000011182 |
| coordinates | chr10:105568091-105572403 |